InVisioning* Lab
*Lab
InVisioning Lab develops methodologies and tools for quantitative biomedical imaging, with the aim of transforming complex biomedical images and signals into reliable, interpretable, and useful information for biomedical research and for the development of advanced healthcare solutions. The group brings together expertise in engineering, mathematics, and ICT to address the characterization of biological tissues in different contexts, combining data acquisition, image processing, mathematical modeling, and artificial intelligence.
The laboratory’s activities are framed within a multiscale and multimodal perspective. On the one hand, the group studies ex vivo images, such as high-resolution histological images, to quantitatively analyze the microstructure of biological tissues. In this area, advanced image processing and AI techniques make it possible to move from predominantly qualitative assessment to more objective, reproducible, and automated descriptions, reducing subjectivity in interpretation and increasing the robustness of analysis workflows.
On the other hand, the laboratory develops and applies in vivo quantitative imaging approaches, including ultrasound and photoacoustic imaging, to obtain non-invasive information on the structural and functional properties of tissues. These methodologies generate large amounts of heterogeneous data, whose interpretation requires mathematical models and algorithms capable of improving their quality, readability, and informative value.
A distinctive feature of InVisioning Lab is its use of AI not only as an automation tool, but also as a means of supporting the quantitative representation and understanding of biological phenomena. For this reason, the group pays particular attention to issues such as reliability, controllability, validation, and algorithm transparency, which are essential in the biomedical field. The goal is not only to achieve high-performing models, but also to build methods that are robust, verifiable, and interpretable.
By integrating data from different imaging modalities and observations at different scales, from tissue microstructure to the in vivo organism, InVisioning Lab aims to develop intelligent solutions capable of transforming the complexity of data into useful, actionable knowledge.
The laboratory’s activities are framed within a multiscale and multimodal perspective. On the one hand, the group studies ex vivo images, such as high-resolution histological images, to quantitatively analyze the microstructure of biological tissues. In this area, advanced image processing and AI techniques make it possible to move from predominantly qualitative assessment to more objective, reproducible, and automated descriptions, reducing subjectivity in interpretation and increasing the robustness of analysis workflows.
On the other hand, the laboratory develops and applies in vivo quantitative imaging approaches, including ultrasound and photoacoustic imaging, to obtain non-invasive information on the structural and functional properties of tissues. These methodologies generate large amounts of heterogeneous data, whose interpretation requires mathematical models and algorithms capable of improving their quality, readability, and informative value.
A distinctive feature of InVisioning Lab is its use of AI not only as an automation tool, but also as a means of supporting the quantitative representation and understanding of biological phenomena. For this reason, the group pays particular attention to issues such as reliability, controllability, validation, and algorithm transparency, which are essential in the biomedical field. The goal is not only to achieve high-performing models, but also to build methods that are robust, verifiable, and interpretable.
By integrating data from different imaging modalities and observations at different scales, from tissue microstructure to the in vivo organism, InVisioning Lab aims to develop intelligent solutions capable of transforming the complexity of data into useful, actionable knowledge.
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Scientific coordinator
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Research team
Research area
Research topics
- Artificial intelligence for biomedical image and signal analysis: development of methods to extract quantitative parameters from biomedical images and signals, transforming complex data into objective and interpretable intelligence
- Ex vivo histological image analysis: study of the microstructure of biological tissues through high-resolution images, using image processing and AI techniques for automated and reproducible analyses
- In vivo photoacoustic and ultrasound imaging: development and application of non-invasive methodologies for the structural and functional characterization of biological tissues
- Mathematical modeling and multimodal integration: use of mathematical models and quantitative algorithms to combine heterogeneous data from different imaging modalities and observation scales
- Reliability, interpretability, and validation of algorithms: study of robust, transparent, and controllable methods, with particular attention to validation and consistency of results in biomedical contexts
Skills
ERC sectors
SDG
Keywords
Research collaborations
- 3D LAB – Virtual design methods and human-machine interaction engineering
- Biomedical Instrumentation and Neuromuscular System Engineering
Pubblicazioni da archivio istituzionale
Publications from the institutional repository
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Barua, Prabal Datta; Goktas, Omer Faruk; Dogan, Sengul; Baygin, Nursena; Baygin, Mehmet; ... (2026)
A new lung disorder detection model based on graphene pattern using respiratory sounds. In: SPEECH COMMUNICATION, vol. 181. ISSN 0167-6393 -
Yildiz, Arif Metehan; Barua, Prabal Datta; Baygin, Mehmet; Dogan, Sengul; Tuncer, ... (2026)
A novel approach using deep belief network patterns and attention binary decomposition for automated community emotion detection. In: BIOMEDICAL SIGNAL PROCESSING AND CONTROL, vol. 116. ISSN 1746-8094 -
Gertych, Arkadiusz; Salvi, Massimo; Mischi, Massimo (2026)
Advances in digital health: Multimodal intelligence and translational impact. In: COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, vol. 273. ISSN 0169-2607 -
Pathan, S.; Shahini, A.; Salvi, M.; Ali, T.; Lewis, J. R.; Molinari, F.; Acharya, U. R. (2026)
Artificial Intelligence in Gastrointestinal Disease Diagnosis: A Systematic Review of Endoscopy, Histology, and Radiology Applications. In: WILEY INTERDISCIPLINARY REVIEWS. DATA MINING AND KNOWLEDGE DISCOVERY, vol. 16. ISSN 1942-4795 -
James, Jimcymol; Gudigar, Anjan; Raghavendra, U.; Samanth, Jyothi; Maithri, M.; ... (2026)
Automated identification of left ventricular hypertrophy using cardiac ultrasound imaging: A systematic review of artificial intelligence driven approaches. In: INFORMATICS IN MEDICINE UNLOCKED, vol. 60. ISSN 2352-9148 -
Salvi, Massimo; Dogan, Sengul; Inamdar, Mahesh Anil; Raghavendra, U.; Gudigar, Anjan; ... (2026)
Evolution of fuzzy logic in medical applications: methods, trends and clinical applications. In: EXPERT SYSTEMS WITH APPLICATIONS, vol. 321. ISSN 0957-4174 -
Ruocco, Gerardina; Marcello, Elena; Paoletti, Camilla; Salvi, Massimo; Zoso, Alice; ... (2026)
Fibrous bioinks for the bioprinting of anisotropic scaffolds with micro-and nanoscale organization as a novel approach for in vitro skeletal muscle engineering. In: INTERNATIONAL JOURNAL OF BIOPRINTING, vol. 12, pp. 323-347. ISSN 2424-8002 -
Chadalavada, Sreeni; Shahini, Alen; Hagiwara, Yuki; Salvi, Massimo; Sharma, Ekta; March, ... (2026)
Impact of Pollution on Mental Health: A Systematic Review of Associations, Methodological Challenges, and Future Directions. In: HEALTH SCIENCE REPORTS, vol. 9. ISSN 2398-8835 -
Loi, Gianfranco; Fusella, Marco; Zara, Stefania; Vagni, Marica; Michielli, Nicola; ... (2026)
Inverse consistency error for validating deformable image registration: an explorative study on computational phantoms. In: PHYSICS AND IMAGING IN RADIATION ONCOLOGY, vol. 37, pp. 1-7. ISSN 2405-6316 -
Bugyi, Lukasz; Schmitner, Nicole; Kimmel Robin, A; Meyer, Dirk; Zhou, Qifa; Haindl, ... (2026)
Lissajous-trajectory scanning optical coherence photoacoustic microscopy for zebrafish larva imaging. In: JPHYS PHOTONICS, vol. 8. ISSN 2515-7647 -
Mohammadi, Afshin; Mohebbi, Alisa; Mirza-Aghazadeh-Attari, Mohammad; Mohammadzadeh, ... (2026)
LymphUs: A multicenter open-access database of lymph node ultrasound images in patients with papillary thyroid carcinoma for clinical and artificial intelligence research. In: DATA IN BRIEF, vol. 66. ISSN 2352-3409 -
Ferraris, Andrea; Branciforti, Francesco; Meiburger, Kristen M.; Veronese, Federica; ... (2026)
No-Reference Quality Assessment of Dermoscopic Images Using Minimal Expert Supervision. In: APPLIED SCIENCES, vol. 16. ISSN 2076-3417 -
Deloria, Abigail J.; Csiszar, Agnes; Deng, Shiyu; Sabbaghi, Mohammad Ali; Branciforti, ... (2026)
Optical coherence photoacoustic microscopy for 3D cancer model imaging with AI-assisted organoid analysis. In: LIGHT, SCIENCE & APPLICATIONS, vol. 15. ISSN 2047-7538 -
Sengur, Abdulkadir; Salvi, Massimo; Barua, Prabal Datta; Deo, Ravinesh; Li, Yan; ... (2026)
QAAR-SIREN: quantum-augmented attention and residual SIREN for time-series forecasting. In: INFORMATION SCIENCES, vol. 754. ISSN 0020-0255 -
Salvi, Massimo; Michielli, Nicola; Mogetta, Alessandro; Gambella, Alessandro; Sengur, ... (2026)
Shifting the Focus of Digital Pathology: The Raising Relevance of Pre-Processing Phase Over Model Complexity. In: IET IMAGE PROCESSING, vol. 20. ISSN 1751-9659 -
Barua, Prabal Datta; Tasci, Burak; Baygin, Mehmet; Dogan, Sengul; Tuncer, Turker; ... (2026)
ShortNeXt: A novel method for accurate classification of colorectal cancer histopathology images. In: COMPUTER VISION AND IMAGE UNDERSTANDING, vol. 265. ISSN 1077-3142 -
Scotto, Manuela; Patti, Roberta; L'Imperio, Vincenzo; Fraggetta, Filippo; Molinari, ... (2026)
SlideInspect: From Pixel-Level Artifact Detection to Actionable Quality Metrics in Digital Pathology. In: INTERNATIONAL JOURNAL OF IMAGING SYSTEMS AND TECHNOLOGY, vol. 36. ISSN 0899-9457 -
Inamdar, Mahesh Anil; Gudigar, Anjan; Raghavendra, U.; Kaprekar, Aryaman; Salvi, ... (2026)
TrustNet: a lightweight network with integrated uncertainty quantification and quantitative explainable AI for ischemic stroke detection in CT images. In: SCIENTIFIC REPORTS, vol. 16. ISSN 2045-2322 -
Nitti, Francesco; Seoni, Silvia; Morello, Alberto; Dolci, Lorenzo; Piazza, Amedeo; ... (2026)
Uncertainty-aware semi-supervised learning for neurosurgical navigation. In: APPLIED SOFT COMPUTING, vol. 197. ISSN 1568-4946 -
Gomez, Carolina; Letizia, Annalisa; Tufano, Vincenza; Molinari, Filippo; Salvi, Massimo (2025)
A cascade approach for the early detection and localization of myocardial infarction in 2D-echocardiography. In: MEDICAL ENGINEERING & PHYSICS, vol. 143. ISSN 1350-4533